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Granagard administration prolongs the survival of human mesenchymal stem cells transplanted into a mouse model of multiple sclerosis.
Frid K, Usmann A, Markovits-Pachter T, Binyamin O, Petrou P,
Kassis I, Karussis D, Gabizon R.
J Neuroimmunol. 2024 Apr 15;389:578313. doi: 10.1016/j.jneuroim.2024.578313.
Epub 2024 Feb 14.
Nano-PSO Administration Attenuates Cognitive and Neuronal Deficits Resulting from Traumatic Brain Injury.
Qubty D, Frid K, Har-Even M, Rubovitch V, Gabizon R, Pick CG.
Molecules. 2022 Apr 23;27(9):2725. doi: 10.3390/molecules27092725.
Comparing anti–aging hallmark activities of Metformin and Nano-PSO in a mouse model of genetic Creutzfeldt-Jakob Disease.
Binyamin O, Frid K, Keller G, Saada, Gabizon R.
Neurobiol Aging. 2022 Feb;110:77-87. doi: 10.1016/j.neurobiolaging.2021.11.001.
Epub 2021 Nov 11.
The effect of GranaGard on cognitive indices in MS patients
Beneficial effects of a nano formulation of pomegranate seed oil, Granagard®, on the cognitive function in multiple sclerosis patients.
P. Petrou MD, A. Ginzberg PhD., O. Binyamin PhD. and D. Karussis MD, PhD.
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Research Details – The Ministry of Health’s Clinical Research Website
Presented at a conference of the Israeli Association of Neurology. December 2019
Also presented at the Greek Neuroimmunological Conference, December 2019
Punica granatum L.-derived omega-5 nanoemulsion improves hepatic steatosis in mice fed a high fat diet by increasing fatty acid utilization in hepatocytes
K. Zamora-López, L. G. Noriega, A. Estanes-Hernández, I. Escalona-Nández, S. Tobón-Cornejo, A. R. Tovar, V. Barbero-Becerra & C. Pérez-Monter
Delay of gCJD aggravation in sick TgMHu2ME199K mice by combining NPC transplantation and Nano-PSO administration.
Neurobiol Aging. 2020 Aug 6;95:231-239. doi: 10.1016/j.neurobiolaging.2020.07.030. Epub ahead of print. PMID: 32861834.
Frid K, Binyamin O, Usman A, Gabizon R.
Brain targeting of 9c,11t-Conjugated Linoleic Acid, a natural calpain inhibitor, preserves memory and reduces Aβ and P25 accumulation in 5XFAD mice.
Sci Rep. 2019 Dec 5;9(1):18437. doi: 10.1038/s41598-019-54971-9. Erratum in: Sci Rep. 2020 Jan 23;10(1):1320. PMID: 31804596; PMCID: PMC6895090.
Binyamin O, Nitzan K, Frid K, Ungar Y, Rosenmann H, Gabizon R.
Mitochondrial dysfunction in preclinical genetic prion disease: A target for preventive treatment?
Neurobiol Dis. 2019 Apr;124:57-66. doi: 10.1016/j.nbd.2018.11.003. Epub 2018 Nov 10. PMID: 30423473.
Keller G, Binyamin O, Frid K, Saada A, Gabizon R
Thanks to the unique development based on the most advanced “nanotechnology” in the world today, GranaGard will be granted a European patent.
Thanks to the unique development based on the most advanced “nanotechnology” in the world today, GranaGard has been granted a U.S. patent.
Continues administration of Nano-PSO significantly increased survival of genetic CJD mice.
Neurobiol Dis. 2017 Dec;108:140-147. doi: 10.1016/j.nbd.2017.08.012. Epub 2017 Aug 25. PMID: 28847567.
Binyamin O, Keller G, Frid K, Larush L, Magdassi S, Gabizon R.
The world’s only dietary supplement containing Nano-Omega 5 antioxidant from a natural source.
Treatment of a multiple sclerosis animal model by a novel nanodrop formulation of a natural antioxidant.
International Journal of Nanomedicine. 2015:10. 7165—7174. 10.2147/IJN.S92704.
Binyamin, Orli & Larush, Liraz & Arush, & Frid, Kati & Keller, Guy & Friedman-Levi, Yael & Ovadia, Haim & Abramsky, Oded & Magdass, Shlomo & Gabizon, Ruth. (2015).
Pomegranate seed oil nanoemulsions for the prevention and treatment of neurodegenerative diseases: the case of genetic CJD.
Nanomedicine. 2014 Aug;10(6):1353-63. doi: 10.1016/j.nano.2014.03.015. Epub 2014 Apr 2. PMID: 24704590.
Mizrahi M, Friedman-Levi Y, Larush L, Frid K, Binyamin O, Dori D, Fainstein N, Ovadia H, Ben-Hur T, Magdassi S, Gabizon R.
GRANALIX is a biotechnology start-up company, founded by Professor Ruth Gabizon – senior researcher from the Department of Neurology at Hadassah University Hospital, Jerusalem – together with Professor Shlomo Magdassi, an international expert in the field of Nanotechnology from the Casali Center, Institute of Chemistry, at the Hebrew University of Jerusalem.
Granalix Bio Technologies Ltd
Yad Harutzim St. 6 Talpiot
Jerusalem, 9342144, Israel
* These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.
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